A two-sample test sensitive to crossing hazards in uncensored and singly censored data.
1985 Sep
Journal Article
Authors:
Stablein, D.M.;
Koutrouvelis, I.A.
Secondary:
Biometrics
Volume:
41
Pagination:
643-52
Issue:
3
PMID:
4074816
Keywords:
Antineoplastic Combined Chemotherapy Protocols; Biometry; Clinical Trials as Topic; Combined Modality Therapy; Follow-Up Studies; Gastrointestinal Neoplasms; Humans; Mathematics
Abstract:
<p>Savage score statistics are employed to develop a test for comparing survival distributions with right-hand singly censored data. The procedure is motivated by the interest in developing a powerful method for determining differences when true survival distributions cross. Examination of small-sample characteristics under the null hypothesis indicate that asymptotic critical values yield a slightly conservative test. Power of the test compares favorably with other criteria, including the modified Smirnov procedure, particularly if there is a single crossing of the survival curves.</p>